Polynucleotides

In the ever-evolving world of aesthetics, new ingredients and formulations emerge daily. It’s important that we to stay informed about industry advancements to keep abreast of patient trends. While familiar substances like hyaluronic acid and poly-l-lactic acid have become commonplace in the industry in the form of fillers, innovation in the aesthetics industry continues to soar with the rise of an exciting newcomer: polynucleotides. With their rapid surge in popularity, we’re exploring your common queries such as ‘what are polynucleotides’ and how you can seamlessly integrate them into your clinic. What Are Polynucleotides? Polynucleotides are the hottest topic of the aesthetic industry at the moment and with their rapid surge in popularity, it’s essential to grasp the essence of these restorative injectables. But what are polynucleotides, exactly, and how can they help resolve your patients’ top concerns? In the world of aesthetics, polynucleotides are known as the future of regenerative injectables – hailed for their ability to rejuvenate and regenerate the skin, similarly to skin boosters like Seventy Hyal 2000. However, unlike skin boosters, injectable polynucleotides are renowned for their wound-healing and bio-stimulating properties. Although similar to skin boosters, polynucleotide injectables are separated and well-recognised for their complex structures and ability to rejuvenate the skin with a natural result. Taking a scientific approach to ‘what are polynucleotides’, these injectables employ filtered, ultra-purified, and sterilised DNA fractions with the aim of rejuvenating the skin. Predominantly derived from salmon DNA*, polynucleotides are designed to stimulate fibroblasts, promoting tissue repair, enhancing cell turnover, increasing elasticity, and augmenting collagen production. Additionally, they possess the ability to soothe inflammation and restore the balance of melanocyte activity (skin pigmentation), resulting in a more even and refreshed skin tone without adding volume like traditional dermal fillers. Also frequently known as PN or PDRN, polynucleotides are categorised as a regenerative treatment with the purpose of revitalising the skin on a deeper level. Each polynucleotide strand consists of a repeating pattern of a sugar molecule and a phosphate group. DNA and RNA represent the two main categories of nucleic acids. In simpler terms, these injectables essentially provide DNA molecules that encourage the skin to repair itself and promote various skin-boosting benefits, both immediate and long-term. This exciting advancement in regenerative medicine focuses on restoring normal cellular function by repairing the skin on a more intense level. Like many other regenerative medicine tools, polynucleotides have a long history of being used in general medicine before their introduction to the world of medical aesthetics with over 90 clinical trials to back this up. Studies have reported their successful treatments with the evidence for polynucleotide’s power remaining undisputed in both the medical and aesthetic fields. What Can Polynucleotides Be Used For? Aside from an increase in search queries for ‘what are polynucleotides’, another question we often see is ‘what can polynucleotides be used for?’. Unlike some injectables, polynucleotides are an exceptionally versatile and all-around treatment. With polynucleotide products developed with a host of concerns in mind, these restorative injectables can be used to treat perceived flaws across the body and face, including the eye area and stretch marks. Excellent at boosting fibroblast production and inducing deep tissue repair processes, polynucleotides enhance the skin’s quality whilst also aiding with other concerns. Some other key usages of polynucleotides include: Acne scarring Skin conditions such as rosacea, melasma and hyperpigmentation Atrophic scarring Alopecia and androgenic hair loss Deep lines and sunken wrinkles Skin rehydration and rejuvenation Elastosis Facial ageing such as sagging and the formation of fine lines Lumpy scars How Long Does It Take for Polynucleotide Injections to Work? Like other injectables, polynucleotides also require a period of downtime and maintenance treatments for optimal efficacy. Whilst this completely depends on your patients aims and the product you choose to use, we recommend that your patient undergoes a course of at least three treatments for maximum results. Again, whilst it may differ from patient to patient, most people notice a difference after 3-5 weeks, with the target results expected from 3+ months after the course of treatment has been issued. By recommending your patient undergo a series of treatments, you can ensure continued active stimulation of fibroblast production which will essentially maximise both the short and long-term results. Moreover, for each treatment, it will depend on the degree of ageing that your patients’ tissue has and its ability to create quality tissue when stimulated by the polynucleotide It’s also crucial for you to remind your patients on the importance of a healthy diet, reducing alcohol consumption and smoking and to also follow a nutritious diet to help repair the skin holistically. What Is the Difference Between Polynucleotides and Dermal Fillers? Despite there being different types of dermal filler, the most well-known and perhaps the most popular types are hyaluronic acid (HA) fillers. The biggest difference between the two injectables is that hyaluronic acid dermal fillers, like the REVOLAX range, work by restoring and adding volume to the skin. With dermal fillers, the results are almost instantaneous with visible contouring and augmentation – often lasting up to 18 months depending on the type of dermal filler used. On the other hand, polynucleotides work to stimulate fibroblasts at a cellular level to improve skin health. Contrarily to hyaluronic acid dermal fillers, whilst polynucleotides can add slight volume to the injected area, their main goal is rejuvenation.In a controlled study comparing the effects of polynucleotides and hyaluronic acid fillers for periocular rejuvenation, results showed that the improvement rates of skin elasticity and hydration decreased over time in both groups. However, the polynucleotide group showed a higher improvement rate in comparison to the hyaluronic acid filler.

Microneedling with Polynucleotides (Vitaran)

This is the perfect alternative treatment to harness the power of polynucleotides with the skin without the use of typical needles and injecting techniques. Microneedling works by encouraging your skin to make more collagen. The idea is that pinpricks from the procedure cause slight injury to the skin and that the skin responds by making new collagen-rich tissue. This new skin tissue is, in turn, more even in tone and texture. It’s normal for the skin to lose collagen via age or injury. By encouraging the skin to make new tissue, there may be more collagen to help make the skin firmer, too. Microneedling is most often used on your face to target: • Acne scars • Age spots (also called “sun spots”) • Fine lines and wrinkles • Large pores • Other types of scars • Reduced skin elasticity • Uneven skin tone Like all cosmetic procedures, microneedling isn’t without risk. The most common side effect is minor skin irritation immediately following the procedure. You may also see redness for a few days. You may not be an ideal candidate for microneedling if you: • Are pregnant/breastfeeding • Have certain skin diseases, such as psoriasis or eczema • Have active acne • Have open wounds • Have had radiation therapy recently • Have a history of skin scars To maintain the results of your treatment, you’ll need multiple sessions and perhaps other complementing treatments. At Scratch Aesthetics all Microneedling Treatments are carried out using Medik8 Medical Grade products including, double cleanse, toner and Hyaluronic Acid Serum A face mask is also applied as part of your treatment. VITARAN is the first 100% quality-controlled polynucleotide injectable. Embodying the highest level of aesthetic innovation and intended for use on the under eye, VITARAN I reduces the signs of aging by improving periocular wrinkles. A bio-revitalising injectable exclusive to Fox Group. As the first 100% quality-controlled polynucleotide, VITARAN Il rejuvenates the skin. Intended for use on the face, neck, hands and décolleté, VITARAN I| aids the stimulation of collagen and elastin. Benefits of VITARAN include: ???? Regenerates and repairs the skin ???? Stimulates collagen at a cellular level ???? Cellular regeneration for better skin quality ???? Skin regeneration, hydration, skin tightening and overall bio-stimulation

£250.00

with a £50.00 deposit
45 mins

VITARAN Face, Neck, Decollete and Hands

VITARAN II is the latest polynucleotide injectable, exclusive to Fox Group. It is the first-ever 100% quality-controlled polynucleotide, embodying the highest level of aesthetic innovation. Derived from 100% purified fragments of salmon DNA, VITARAN is a bio-revitalising skin injectable that has anti-inflammatory benefits. By stimulating the synthesis of collagen, elastin, and hyaluronic acid, VITARAN aids in skin rejuvenation and repair, while simultaneously stimulating the production of fibroblasts and other growth factors. Key Features CE-marked, meaning that VITARAN has been assessed to meet high safety, health, and environmental protection requirements. Restores skin to its optimal health Formulated with 100% filtered, ultra-purified, sterilised salmon DNA Can be used alongside other injectables including skin boosters like Seventy Hyal 2000 Anti-inflammatory properties Has shown efficacy in scar improvement Combats free radical damage Treatment Areas VITARAN II works to efficaciously regulate the biological process of living cells and repairs the skin’s natural barrier. Treatment areas include: Face Neck Hands Décolleté Composition Polynucleotide sodium 20mg/ml (PN 2%)

£220.00

with a £50.00 deposit
30 mins

VITARAN Face, Neck, Decollete and Hands Three Sessions

VITARAN II is the latest polynucleotide injectable, exclusive to Fox Group. It is the first-ever 100% quality-controlled polynucleotide, embodying the highest level of aesthetic innovation. Derived from 100% purified fragments of salmon DNA, VITARAN is a bio-revitalising skin injectable that has anti-inflammatory benefits. By stimulating the synthesis of collagen, elastin, and hyaluronic acid, VITARAN aids in skin rejuvenation and repair, while simultaneously stimulating the production of fibroblasts and other growth factors. Key Features CE-marked, meaning that VITARAN has been assessed to meet high safety, health, and environmental protection requirements. Restores skin to its optimal health Formulated with 100% filtered, ultra-purified, sterilised salmon DNA Can be used alongside other injectables including skin boosters like Seventy Hyal 2000 Anti-inflammatory properties Has shown efficacy in scar improvement Combats free radical damage Treatment Areas VITARAN II works to efficaciously regulate the biological process of living cells and repairs the skin’s natural barrier. Treatment areas include: Face Neck Hands Décolleté Composition Polynucleotide sodium 20mg/ml (PN 2%)

£600.00

with a £50.00 deposit
30 mins

VITARAN Face, Neck, Decollete and Hands Two Sessions

VITARAN II is the latest polynucleotide injectable, exclusive to Fox Group. It is the first-ever 100% quality-controlled polynucleotide, embodying the highest level of aesthetic innovation. Derived from 100% purified fragments of salmon DNA, VITARAN is a bio-revitalising skin injectable that has anti-inflammatory benefits. By stimulating the synthesis of collagen, elastin, and hyaluronic acid, VITARAN aids in skin rejuvenation and repair, while simultaneously stimulating the production of fibroblasts and other growth factors. Key Features CE-marked, meaning that VITARAN has been assessed to meet high safety, health, and environmental protection requirements. Restores skin to its optimal health Formulated with 100% filtered, ultra-purified, sterilised salmon DNA Can be used alongside other injectables including skin boosters like Seventy Hyal 2000 Anti-inflammatory properties Has shown efficacy in scar improvement Combats free radical damage Treatment Areas VITARAN II works to efficaciously regulate the biological process of living cells and repairs the skin’s natural barrier. Treatment areas include: Face Neck Hands Décolleté Composition Polynucleotide sodium 20mg/ml (PN 2%)

£410.00

with a £50.00 deposit
30 mins

VITARAN Eyes

VITARAN I is the latest polynucleotide injectable, exclusive to Fox Group. It is the first-ever 100% quality-controlled polynucleotide, embodying the highest level of aesthetic innovation. Derived from 100% purified fragments of salmon DNA, VITARAN is a bio-revitalising skin injectable that has anti-inflammatory benefits. By stimulating the synthesis of collagen, elastin, and hyaluronic acid, VITARAN aids in skin rejuvenation and repair, while simultaneously stimulating the production of fibroblasts and other growth factors. Key Features: CE-marked, meaning that VITARAN I has been assessed to meet high safety, health, and environmental protection requirements. Indicated for the improvement of periocular wrinkles Formulated with 100% filtered, ultra-purified, sterilised salmon DNA Can be used alongside other injectables including skin boosters like Seventy Hyal 2000 Anti-inflammatory properties Combats free radical damage Treatment Areas: VITARAN I works to efficaciously regulate the biological process of living cells and repairs the skin’s natural barrier. Treatment areas include: Under eye (periorbital area) Composition: Polynucleotide sodium 20mg/ml (PN 2%)

£180.00

with a £50.00 deposit
30 mins

VITARAN Eyes Two Sessions

VITARAN I is the latest polynucleotide injectable, exclusive to Fox Group. It is the first-ever 100% quality-controlled polynucleotide, embodying the highest level of aesthetic innovation. Derived from 100% purified fragments of salmon DNA, VITARAN is a bio-revitalising skin injectable that has anti-inflammatory benefits. By stimulating the synthesis of collagen, elastin, and hyaluronic acid, VITARAN aids in skin rejuvenation and repair, while simultaneously stimulating the production of fibroblasts and other growth factors. Key Features: CE-marked, meaning that VITARAN I has been assessed to meet high safety, health, and environmental protection requirements. Indicated for the improvement of periocular wrinkles Formulated with 100% filtered, ultra-purified, sterilised salmon DNA Can be used alongside other injectables including skin boosters like Seventy Hyal 2000 Anti-inflammatory properties Combats free radical damage Treatment Areas: VITARAN I works to efficaciously regulate the biological process of living cells and repairs the skin’s natural barrier. Treatment areas include: Under eye (periorbital area) Composition: Polynucleotide sodium 20mg/ml (PN 2%)

£330.00

with a £50.00 deposit
30 mins

VITARAN Eyes Three Sessions

VITARAN I is the latest polynucleotide injectable, exclusive to Fox Group. It is the first-ever 100% quality-controlled polynucleotide, embodying the highest level of aesthetic innovation. Derived from 100% purified fragments of salmon DNA, VITARAN is a bio-revitalising skin injectable that has anti-inflammatory benefits. By stimulating the synthesis of collagen, elastin, and hyaluronic acid, VITARAN aids in skin rejuvenation and repair, while simultaneously stimulating the production of fibroblasts and other growth factors. Key Features: CE-marked, meaning that VITARAN I has been assessed to meet high safety, health, and environmental protection requirements. Indicated for the improvement of periocular wrinkles Formulated with 100% filtered, ultra-purified, sterilised salmon DNA Can be used alongside other injectables including skin boosters like Seventy Hyal 2000 Anti-inflammatory properties Combats free radical damage Treatment Areas: VITARAN I works to efficaciously regulate the biological process of living cells and repairs the skin’s natural barrier. Treatment areas include: Under eye (periorbital area) Composition: Polynucleotide sodium 20mg/ml (PN 2%)

£450.00

with a £50.00 deposit
30 mins

aesPlla (Poly-L-Lactic Acid)

THE FUTURE OF RESTORATIVE INJECTABLES aesPlla® is a Poly-L-Lactic Acid-based (PLLA) filler and collagen stimulator. Formulated with a biocompatible and biodegradable synthetic polymer, the injectable stimulates collagen production to help volumise and smooth. Offering gradual results, the bio-stimulatory treatment works to correct the appearance of shallow to deep nasolabial fold contour deficiencies and facial wrinkles. Subsequent results may be observed from four weeks post-treatment, lasting up to 3 years. Key Features: Ideal for patients aged 30+ Stimulates collagen to increase skin volume Effects of aesPlla® can be observed from 4 weeks post-injection Gradual and natural-looking results. Results last up to 3 years Creates a softer and more natural-looking result than traditional fillers Treatment Areas: Shallow to deep facial wrinkles Nasolabial folds Temple Cheeks Deep dermal deficiencies Marionette lines Sagging jowls Scarring Natural Looking Results aesPlla® volumises the skin through collagen regeneration, offering softer and more natural-looking results than other dermal fillers. Treatment results are gradual and are enhanced over time, as the bio-stimulatory filler harmonises with the skin’s natural collagen production to create a fresher and smoother appearance. Lasting Volume aesPlla® offers long-term rejuvenation. Treatment results are gradual and longer-lasting than those of hyaluronic acid dermal fillers. Initial results will begin to show at around four weeks post-treatment, lasting for up to 3 years. aesPlla® is a semi-permanent treatment that naturally biodegrades within the skin over time. Collagen Regeneration Collagen loss occurs at a rate of 1% per year after the age of 30, leading to facial volume loss. aesPlla® combats this depletion through the bio-stimulation of collagen regeneration for fast and effective rejuvenation. Innovative Formulation aesPlla®’s advanced formulation offers superior product quality, with a low risk of migration. The streamlined particle structure ensures even distribution, mitigating the risk of complications associated with traditional bio-stimulatory fillers. The formula does not attract water and can be administered smoothly with a softer injection force, for enhanced patient comfort. Treatments aesPlla® provides a natural-looking solution to volume loss, utilising PLLA to stimulate collagen production for gradual volumisation and rejuvenation. The treatment is ideal for patients 30+ who are concerned with skin ageing, dermal deficiencies, laxity and areas prone to volume loss, such as the cheeks, temples, nasolabial and marionette lines. Treating facial volume loss using aesPlla® is a gradual process that requires 3-4 treatments, spaced six weeks apart, in order to achieve optimal volumisation. Some patient may only require 2 sessions.

£280.00

with a £50.00 deposit
30 mins

aesPlla (Poly-L-Lactic Acid) Course of 3

THE FUTURE OF RESTORATIVE INJECTABLES aesPlla® is a Poly-L-Lactic Acid-based (PLLA) filler and collagen stimulator. Formulated with a biocompatible and biodegradable synthetic polymer, the injectable stimulates collagen production to help volumise and smooth. Offering gradual results, the bio-stimulatory treatment works to correct the appearance of shallow to deep nasolabial fold contour deficiencies and facial wrinkles. Subsequent results may be observed from four weeks post-treatment, lasting up to 3 years. Key Features: Ideal for patients aged 30+ Stimulates collagen to increase skin volume Effects of aesPlla® can be observed from 4 weeks post-injection Gradual and natural-looking results. Results last up to 3 years Creates a softer and more natural-looking result than traditional fillers Treatment Areas: Shallow to deep facial wrinkles Nasolabial folds Temple Cheeks Deep dermal deficiencies Marionette lines Sagging jowls Scarring Natural Looking Results aesPlla® volumises the skin through collagen regeneration, offering softer and more natural-looking results than other dermal fillers. Treatment results are gradual and are enhanced over time, as the bio-stimulatory filler harmonises with the skin’s natural collagen production to create a fresher and smoother appearance. Lasting Volume aesPlla® offers long-term rejuvenation. Treatment results are gradual and longer-lasting than those of hyaluronic acid dermal fillers. Initial results will begin to show at around four weeks post-treatment, lasting for up to 3 years. aesPlla® is a semi-permanent treatment that naturally biodegrades within the skin over time. Collagen Regeneration Collagen loss occurs at a rate of 1% per year after the age of 30, leading to facial volume loss. aesPlla® combats this depletion through the bio-stimulation of collagen regeneration for fast and effective rejuvenation. Innovative Formulation aesPlla®’s advanced formulation offers superior product quality, with a low risk of migration. The streamlined particle structure ensures even distribution, mitigating the risk of complications associated with traditional bio-stimulatory fillers. The formula does not attract water and can be administered smoothly with a softer injection force, for enhanced patient comfort. Treatments aesPlla® provides a natural-looking solution to volume loss, utilising PLLA to stimulate collagen production for gradual volumisation and rejuvenation. The treatment is ideal for patients 30+ who are concerned with skin ageing, dermal deficiencies, laxity and areas prone to volume loss, such as the cheeks, temples, nasolabial and marionette lines. Treating facial volume loss using aesPlla® is a gradual process that requires 3-4 treatments, spaced six weeks apart, in order to achieve optimal volumisation. Some patient may only require 2 sessions.

£750.00

with a £50.00 deposit
30 mins

Nucleofill Eyes

As the regenerative injectables category continues to grow, more polynucleotide injectables are added to the market almost daily. One of our favourite brands of polynucleotide injectables is Nucleofill. The Nucleofill range is a specialised collection of skin booster treatments with different objectives to help achieve an array of goals. These skin boosters act on three different levels: lifting, antioxidant, and hydrating. Nucleofill is the new line of natural polynucleotide-based, bio-stimulating gels developed with a high viscosity for protecting and rejuvenating the skin. Perhaps surprisingly for a skin booster, it is not formulated with hyaluronic acid (HA). Instead, the Nucleofill product range contains high molecular weight polynucleotide chains. The polynucleotide chains activate two types of membrane receptors in the skin’s fibroblasts. Or rather, Receptor CD39 and Receptor CD40. As a result, the two main effects on the skin include the stimulation of type 1 collagen production and the maturation of fibroblasts in the myofibroblasts. Moreover, the polynucleotide chains have specialised biochemical peculiarities that give the product high viscoelasticity and the ability to bind to a considerable amount of water molecules. Additionally, Nucleofill’s hydrophilic ability allows the injectable to provide an intense moisture surge to the skin and deep hydration in the tissue. In addition to Nucleofill’s long list of benefits, the skin-boosting injection also has an impressive bio-stimulating effect on the skin This scientifically proven skin bio stimulation method contains polynucleotides that stimulate the skin to rebuild using a three-way mechanism. Even though the Nucleofill range promises similar benefits, each singular product within the range is highly specialised to help achieve a different criterion. How frequently should I undergo a Nucleofill treatment? It is recommended to undergo a series of 3-4 treatments every 2-4 weeks for the best results. How long can the results of Nucleofill last? Results are expected to last up to 1-2 years. Nucleofill Soft Plus works to renew and refresh the skin around the eyes for a brighter and firmer appearance. Nucleofill Soft Plus is a subtler alternative to tear trough filler and helps decrease lower eyelid puffiness, fine lines, wrinkles and volume loss. This treatment is safe for all skin types and can be done in combination with other treatments. Nucleofill Soft Plus is a subtler alternative to tear trough filler and is intended to help decrease lower eyelid puffiness, fine lines, wrinkles, and volume loss. This treatment is safe for all skin types and can be done in combination with other treatments. Nucleofill Soft Plus further works to renew and refresh the skin around the eyes for a brighter and firmer appearance – specifically created to improve the trophism of the periocular area. Key Features: Regenerates the skin in the periocular area Formulated with a bio-restructuring gel composed of low molecular weight polynucleotide chain fragments Based on highly purified, naturally derived polynucleotides Developed with a highly purified Polynucleotide matrix able to activate processes of bio-regeneration in the skin both at a deep level and in the dermis Improvement of superficial wrinkles without the use of fillers Can be used as a pre and post-surgical treatment (such as Blepharoplasty, surgical eye lift, laser Treatment Areas: Under eye bags Fine lines around the eye Dark circles The periocular area

£180.00

with a £50.00 deposit
30 mins

Nucleofill Eyes Two Treatments

As the regenerative injectables category continues to grow, more polynucleotide injectables are added to the market almost daily. One of our favourite brands of polynucleotide injectables is Nucleofill. The Nucleofill range is a specialised collection of skin booster treatments with different objectives to help achieve an array of goals. These skin boosters act on three different levels: lifting, antioxidant, and hydrating. Nucleofill is the new line of natural polynucleotide-based, bio-stimulating gels developed with a high viscosity for protecting and rejuvenating the skin. Perhaps surprisingly for a skin booster, it is not formulated with hyaluronic acid (HA). Instead, the Nucleofill product range contains high molecular weight polynucleotide chains. The polynucleotide chains activate two types of membrane receptors in the skin’s fibroblasts. Or rather, Receptor CD39 and Receptor CD40. As a result, the two main effects on the skin include the stimulation of type 1 collagen production and the maturation of fibroblasts in the myofibroblasts. Moreover, the polynucleotide chains have specialised biochemical peculiarities that give the product high viscoelasticity and the ability to bind to a considerable amount of water molecules. Additionally, Nucleofill’s hydrophilic ability allows the injectable to provide an intense moisture surge to the skin and deep hydration in the tissue. In addition to Nucleofill’s long list of benefits, the skin-boosting injection also has an impressive bio-stimulating effect on the skin This scientifically proven skin bio stimulation method contains polynucleotides that stimulate the skin to rebuild using a three-way mechanism. Even though the Nucleofill range promises similar benefits, each singular product within the range is highly specialised to help achieve a different criterion. How frequently should I undergo a Nucleofill treatment? It is recommended to undergo a series of 3-4 treatments every 2-4 weeks for the best results. How long can the results of Nucleofill last? Results are expected to last up to 1-2 years. Nucleofill Soft Plus works to renew and refresh the skin around the eyes for a brighter and firmer appearance. Nucleofill Soft Plus is a subtler alternative to tear trough filler and helps decrease lower eyelid puffiness, fine lines, wrinkles and volume loss. This treatment is safe for all skin types and can be done in combination with other treatments. Nucleofill Soft Plus is a subtler alternative to tear trough filler and is intended to help decrease lower eyelid puffiness, fine lines, wrinkles, and volume loss. This treatment is safe for all skin types and can be done in combination with other treatments. Nucleofill Soft Plus further works to renew and refresh the skin around the eyes for a brighter and firmer appearance – specifically created to improve the trophism of the periocular area. Key Features: Regenerates the skin in the periocular area Formulated with a bio-restructuring gel composed of low molecular weight polynucleotide chain fragments Based on highly purified, naturally derived polynucleotides Developed with a highly purified Polynucleotide matrix able to activate processes of bio-regeneration in the skin both at a deep level and in the dermis Improvement of superficial wrinkles without the use of fillers Can be used as a pre and post-surgical treatment (such as Blepharoplasty, surgical eye lift, laser Treatment Areas: Under eye bags Fine lines around the eye Dark circles The periocular area *This option is for 2 treatments spaces 3-4 weeks apart ** Full payment to be made prior to second appointment being booked

£330.00

with a £50.00 deposit
30 mins

Nucleofill Eyes Three Treatments

As the regenerative injectables category continues to grow, more polynucleotide injectables are added to the market almost daily. One of our favourite brands of polynucleotide injectables is Nucleofill. The Nucleofill range is a specialised collection of skin booster treatments with different objectives to help achieve an array of goals. These skin boosters act on three different levels: lifting, antioxidant, and hydrating. Nucleofill is the new line of natural polynucleotide-based, bio-stimulating gels developed with a high viscosity for protecting and rejuvenating the skin. Perhaps surprisingly for a skin booster, it is not formulated with hyaluronic acid (HA). Instead, the Nucleofill product range contains high molecular weight polynucleotide chains. The polynucleotide chains activate two types of membrane receptors in the skin’s fibroblasts. Or rather, Receptor CD39 and Receptor CD40. As a result, the two main effects on the skin include the stimulation of type 1 collagen production and the maturation of fibroblasts in the myofibroblasts. Moreover, the polynucleotide chains have specialised biochemical peculiarities that give the product high viscoelasticity and the ability to bind to a considerable amount of water molecules. Additionally, Nucleofill’s hydrophilic ability allows the injectable to provide an intense moisture surge to the skin and deep hydration in the tissue. In addition to Nucleofill’s long list of benefits, the skin-boosting injection also has an impressive bio-stimulating effect on the skin This scientifically proven skin bio stimulation method contains polynucleotides that stimulate the skin to rebuild using a three-way mechanism. Even though the Nucleofill range promises similar benefits, each singular product within the range is highly specialised to help achieve a different criterion. How frequently should I undergo a Nucleofill treatment? It is recommended to undergo a series of 3-4 treatments every 2-4 weeks for the best results. How long can the results of Nucleofill last? Results are expected to last up to 1-2 years. Nucleofill Soft Plus works to renew and refresh the skin around the eyes for a brighter and firmer appearance. Nucleofill Soft Plus is a subtler alternative to tear trough filler and helps decrease lower eyelid puffiness, fine lines, wrinkles and volume loss. This treatment is safe for all skin types and can be done in combination with other treatments. Nucleofill Soft Plus is a subtler alternative to tear trough filler and is intended to help decrease lower eyelid puffiness, fine lines, wrinkles, and volume loss. This treatment is safe for all skin types and can be done in combination with other treatments. Nucleofill Soft Plus further works to renew and refresh the skin around the eyes for a brighter and firmer appearance – specifically created to improve the trophism of the periocular area. Key Features: Regenerates the skin in the periocular area Formulated with a bio-restructuring gel composed of low molecular weight polynucleotide chain fragments Based on highly purified, naturally derived polynucleotides Developed with a highly purified Polynucleotide matrix able to activate processes of bio-regeneration in the skin both at a deep level and in the dermis Improvement of superficial wrinkles without the use of fillers Can be used as a pre and post-surgical treatment (such as Blepharoplasty, surgical eye lift, laser Treatment Areas: Under eye bags Fine lines around the eye Dark circles The periocular area *This option is for 3 treatments spaces 3-4 weeks apart - session 2 and 3 to be booked after each session ** Full payment to be made prior to second appointment being booked

£450.00

with a £50.00 deposit
30 mins